Therapy-related, mixed phenotype acute leukemia with t(1;21)(p36;q22) and RUNX1 rearrangement
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چکیده
منابع مشابه
Mixed-phenotype acute leukemia treated with decitabine
Copyright © 2016 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. pISSN 1226-3303 eISSN 2005-664...
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which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Mixed-phenotype acute leukemia (MPAL) is a rare but difficult to treat hematologic malignancy with immuno-phenotypic co-expression of at least two cell lineages, or with only rare cases involving all three lineages, e.g. myeloid with B-or T-lymphoid or all t...
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Mixed-phenotype acute leukemia (MPAL) encompasses a heterogeneous group of rare leukemias in which assigning a single lineage of origin is not possible. A variety of different terms and classification systems have been used historically to describe this entity. MPAL is currently defined by a limited set of lineage-specific markers proposed in the 2008 World Health Organization monograph on clas...
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Mixed phenotype acute leukemia (MPAL) includes biphenotypic and bilineal types of leukemia, which constitute rare subtypes that require individualized therapy. Outcomes in Moroccan patients with MPAL are unknown. Among 1264 patients with acute leukemia, 20 were classified as having MPAL, including 17 with biphenotypic acute leukemia (1.3%) and 3 with bilineal leukemia (0.2%). There were 8 adult...
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ژورنال
عنوان ژورنال: Cancer Genetics and Cytogenetics
سال: 2010
ISSN: 0165-4608
DOI: 10.1016/j.cancergencyto.2010.05.011